InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Mtfp1

Summary

InnateDB Protein

IDBP-141638.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Mtfp1

Protein Name

mitochondrial fission process 1

Synonyms

1700020C11Rik; 2610507A21Rik; AV005788; Mtp18;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000004868

InnateDB Gene

IDBG-141636 (Mtfp1)

Protein Structure

UniProt Annotation

Function

Involved in the mitochondrial division probably by regulating membrane fission. Loss-of-function leads to apoptosis (By similarity). {ECO:0000250}.

Subcellular Localization

Mitochondrion inner membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function

Biological Process

GO:0000266	mitochondrial fission
GO:0006915	apoptotic process
GO:0007006	mitochondrial membrane organization

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:1916686

InterPro

IPR019560 Mitochondrial 18kDa protein

PFAM

PF10558

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9CRB8

PhosphoSite

PhosphoSite-

TrEMBL

Q91X54

UniProt Splice Variant

Entrez Gene

67900

UniGene

Mm.41719

RefSeq

NP_080719

MGI ID

MGI Symbol

Mtfp1

OMIM

CCDS

CCDS24376

HPRD

IMGT

EMBL

AK006148 AK010971 AK012058 AK078381 BC012242 BC058737

GenPept

AAH12242 AAH58737 BAB24432 BAB27300 BAB27999 BAC37244