InnateDB Protein
|
IDBP-142169.6
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
Il1f9
|
Protein Name
|
interleukin 1 family, member 9
|
Synonyms
|
|
Species
|
Mus musculus
|
Ensembl Protein
|
ENSMUSP00000053391
|
InnateDB Gene
|
IDBG-142167 (Il1f9)
|
Protein Structure
|
|
Function |
Function as an agonist of NF-kappa B activation through the orphan IL-1-receptor-related protein 2/IL1RL2. Could constitute part of an independent signaling system analogous to interleukin-1 alpha (IL-1A), beta (IL-1B) receptor agonist and interleukin-1 receptor type I (IL-1R1), that is present in epithelial barriers and takes part in local inflammatory response (By similarity). {ECO:0000250}.
|
Subcellular Localization |
Secreted {ECO:0000250}.
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
1
[view]
|
Protein-DNA |
0
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
|
|
Molecular Function |
|
Biological Process |
GO:0001819
|
positive regulation of cytokine production
|
GO:0032755
|
positive regulation of interleukin-6 production
|
|
Cellular Component |
|
PDB ID |
MGI:2449929
|
InterPro |
IPR000975
Interleukin-1 family
IPR008996
Cytokine, IL-1-like
|
PFAM |
PF00340
|
PRINTS |
PR00264
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q8R460
|
PhosphoSite |
PhosphoSite-Q3U0P4
|
TrEMBL |
Q3U0P4
|
UniProt Splice Variant |
|
Entrez Gene |
215257
|
UniGene |
Mm.249379
|
RefSeq |
NP_705731
|
MGI ID |
|
MGI Symbol |
Il1f9
|
OMIM |
|
CCDS |
CCDS50518
|
HPRD |
|
IMGT |
|
EMBL |
AK081783
AK156687
AL732430
AY071843
BC116227
BC116228
CH466542
|
GenPept |
AAI16228
AAI16229
AAL67153
BAE33808
BAE43375
EDL08162
|
|
|