Version 5.4
Mus musculus Protein: Cdc45
Summary
InnateDB Protein IDBP-142239.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cdc45
Protein Name cell division cycle 45 homolog (S. cerevisiae)
Synonyms Cdc45l;
Species Mus musculus
Ensembl Protein ENSMUSP00000000028
InnateDB Gene IDBG-142237 (Cdc45)
Protein Structure
UniProt Annotation
Function Required for initiation of chromosomal DNA replication.
Subcellular Localization Nucleus.
Disease Associations
Tissue Specificity Widely expressed.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 31 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006270 DNA replication initiation
GO:0007049 cell cycle
Cellular Component
GO:0005634 nucleus
GO:0005813 centrosome
Protein Structure and Domains
PDB ID MGI:1338073
InterPro IPR003874 CDC45 family
PFAM PF02724
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Z1X9
PhosphoSite PhosphoSite-Q9Z1X9
TrEMBL Q3UI99
UniProt Splice Variant
Entrez Gene 12544
UniGene Mm.1248
RefSeq NP_033992
MGI ID
MGI Symbol Cdc45
OMIM
CCDS CCDS28027
HPRD
IMGT
EMBL AC083895 AF081536 AF081537 AF081538 AF081539 AF098068 AJ223729 AK147013 BC028635 CH466521
GenPept AAC95057 AAD08999 AAD09000 AAD09001 AAD09002 AAH28635 BAE27607 CAA11531 EDK97534

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca