Version 5.4
| Mus musculus Protein: Il1f10 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-142316.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Il1f10 | ||||||||
| Protein Name | interleukin 1 family, member 10 | ||||||||
| Synonyms | |||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000063004 | ||||||||
| InnateDB Gene | IDBG-142314 (Il1f10) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Cytokine with immunomodulatory activity. Alone, does not induce cytokine production, but reduces IL22 and IL17A production by T-cells in response to heat-killed Candida albicans. Reduces IL36G-induced production of IL8 by peripheral blood mononuclear cells. Increases IL6 production by dendritic cells stimulated by bacterial lipopolysaccharides (LPS). Ligand for IL-36R/IL1RL2 (By similarity). {ECO:0000250}. | ||||||||
| Subcellular Localization | Secreted {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:2652548 | ||||||||
| InterPro |
IPR000975
Interleukin-1 family IPR003297 Interleukin-1 receptor antagonist / Interleukin-36 IPR008996 Cytokine, IL-1-like |
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| PFAM |
PF00340
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| PRINTS |
PR00264
PR01360 |
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| PIRSF | |||||||||
| SMART | |||||||||
| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q8R459 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | Q3KNF2 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 215274 | ||||||||
| UniGene | Mm.218750 | ||||||||
| RefSeq | NP_694717 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Il1f10 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS15735 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AY071844 BC107311 BC107312 CH466542 | ||||||||
| GenPept | AAI07312 AAI07313 AAL67155 EDL08168 | ||||||||