Version 5.4
Homo sapiens Protein: SLTM
Summary
InnateDB Protein IDBP-14280.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLTM
Protein Name SAFB-like, transcription modulator
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000369887
InnateDB Gene IDBG-14278 (SLTM)
Protein Structure
UniProt Annotation
Function When overexpressed, acts as a general inhibitor of transcription that eventually leads to apoptosis. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}. Note=Detected in punctate structures. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006915 apoptotic process
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR000504 RNA recognition motif domain
IPR003034 SAP domain
PFAM PF00076
PF02037
PRINTS
PIRSF
SMART SM00360
SM00513
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NWH9
PhosphoSite PhosphoSite-Q9NWH9
TrEMBL H0YKH2
UniProt Splice Variant
Entrez Gene 79811
UniGene Hs.512932
RefSeq NP_079031
HUGO HGNC:20709
OMIM
CCDS CCDS10168
HPRD 07819
IMGT
EMBL AC025918 AC090515 AK000867 AK023275 AK024710 AK055195 AK291423 AL834297 BC014944 BC046119 BC108656 BC140851 CH471082
GenPept AAH14944 AAH46119 AAI08657 AAI40852 BAA91401 BAB14502 BAB14971 BAF84112 BAG51484 CAH56362 EAW77550 EAW77551 EAW77552 EAW77553

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca