InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Rasl10a

Summary

InnateDB Protein

IDBP-144058.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rasl10a

Protein Name

RAS-like, family 10, member A

Synonyms

2210403B10Rik; AI852688;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000048453

InnateDB Gene

IDBG-144056 (Rasl10a)

Protein Structure

UniProt Annotation

Function

Potent inhibitor of cellular proliferation. {ECO:0000250}.

Subcellular Localization

Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Nucleus, nucleolus {ECO:0000250}. Note=May cycle in and out of the nucleolus in a GTP-dependent manner. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005525	GTP binding

Biological Process

GO:0006184	GTP catabolic process
GO:0007165	signal transduction
GO:0007264	small GTPase mediated signal transduction
GO:0008150	biological_process
GO:0015031	protein transport

Cellular Component

GO:0005575	cellular_component
GO:0005622	intracellular
GO:0005730	nucleolus
GO:0005886	plasma membrane
GO:0016020	membrane

Protein Structure and Domains

PDB ID

MGI:1922918

InterPro

IPR001806 Small GTPase superfamily
IPR003578 Small GTPase superfamily, Rho type
IPR003579 Small GTPase superfamily, Rab type
IPR013684 Mitochondrial Rho-like
IPR020849 Small GTPase superfamily, Ras type
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00071
PF08477

PRINTS

PR00449

PIRSF

SMART

SM00174
SM00175
SM00173

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt