InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Spink5

Summary

InnateDB Protein

IDBP-144111.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Spink5

Protein Name

serine peptidase inhibitor, Kazal type 5

Synonyms

2310065D10Rik; AV238912; LEKT1; LETK1; VAKT1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000066214

InnateDB Gene

IDBG-144109 (Spink5)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004867	serine-type endopeptidase inhibitor activity
GO:0005515	protein binding
GO:0030414	peptidase inhibitor activity

Biological Process

GO:0009913	epidermal cell differentiation
GO:0010951	negative regulation of endopeptidase activity
GO:0030155	regulation of cell adhesion
GO:0045087	innate immune response (InnateDB)
GO:0045861	negative regulation of proteolysis
GO:1902572	negative regulation of serine-type peptidase activity

Cellular Component

GO:0005737	cytoplasm
GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0005829	cytosol
GO:0005938	cell cortex
GO:0048471	perinuclear region of cytoplasm
GO:0070062	extracellular vesicular exosome
GO:0097209	epidermal lamellar body