Version 5.4
| Mus musculus Protein: Myot | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-144449.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Myot | ||||||||
| Protein Name | myotilin | ||||||||
| Synonyms | 5530402I04Rik; Ttid; | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000025349 | ||||||||
| InnateDB Gene | IDBG-144447 (Myot) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Component of a complex of multiple actin cross-linking proteins. Involved in the control of myofibril assembly and stability at the Z lines in muscle cells (By similarity). {ECO:0000250}. | ||||||||
| Subcellular Localization | Cell membrane, sarcolemma {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, myofibril, sarcomere, Z line {ECO:0000250}. Note=Sarcomeric, also localized to the sarcolemma. Colocalizes with MYOZ1 at the Z-lines of skeletal muscle (By similarity). {ECO:0000250}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Expressed in skeletal muscle (at protein level). {ECO:0000269PubMed:17074808}. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:1889800 | ||||||||
| InterPro |
IPR003598
Immunoglobulin subtype 2 IPR003599 Immunoglobulin subtype IPR007110 Immunoglobulin-like domain IPR013098 Immunoglobulin I-set IPR013106 Immunoglobulin V-set domain |
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| PFAM |
PF07679
PF07686 |
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| PRINTS | |||||||||
| PIRSF | |||||||||
| SMART |
SM00408
SM00409 |
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q9JIF9 | ||||||||
| PhosphoSite | PhosphoSite-Q9JIF9 | ||||||||
| TrEMBL | A0A509 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 58916 | ||||||||
| UniGene | Mm.474632 | ||||||||
| RefSeq | NP_001028793 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Myot | ||||||||
| OMIM | |||||||||
| CCDS | CCDS29228 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AF230979 BC016214 BC064052 CH466528 | ||||||||
| GenPept | AAF76465 AAH16214 AAH64052 EDL10000 | ||||||||