Version 5.4
| Mus musculus Protein: Igsf1 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-144497.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Igsf1 | ||||||||
| Protein Name | immunoglobulin superfamily, member 1 | ||||||||
| Synonyms | |||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000071919 | ||||||||
| InnateDB Gene | IDBG-144491 (Igsf1) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Seems to be a coreceptor in inhibin signaling, but seems not to be a high-affinity inhibin receptor. Antagonizes activin A signaling in the presence or absence of inhibin B. Necessary to mediate a specific antagonistic effect of inhibin B on activin- stimulated transcription (By similarity). {ECO:0000250}. | ||||||||
| Subcellular Localization | Isoform 1: Membrane {ECO:0000305}; Multi- pass membrane protein {ECO:0000305}.Isoform 2: Membrane {ECO:0000305}; Multi- pass membrane protein {ECO:0000305}.Isoform 3: Membrane {ECO:0000305}; Multi- pass membrane protein {ECO:0000305}.Isoform 4: Secreted {ECO:0000305}.Isoform 5: Secreted {ECO:0000305}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:2147913 | ||||||||
| InterPro |
IPR003598
Immunoglobulin subtype 2 IPR003599 Immunoglobulin subtype IPR007110 Immunoglobulin-like domain |
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| PFAM | |||||||||
| PRINTS | |||||||||
| PIRSF | |||||||||
| SMART |
SM00408
SM00409 |
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q7TQA1 | ||||||||
| PhosphoSite | PhosphoSite-Q7TQA1 | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 209268 | ||||||||
| UniGene | Mm.405513 | ||||||||
| RefSeq | NP_899178 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Igsf1 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS40966 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AK030452 AK129126 AY227771 AY227772 AY227773 AY227774 | ||||||||
| GenPept | AAP57079 AAP57080 AAP57081 AAP57082 BAC26969 BAC97936 | ||||||||