Version 5.4
Homo sapiens Protein: SCARA3
Summary
InnateDB Protein IDBP-14453.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SCARA3
Protein Name scavenger receptor class A, member 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000337985
InnateDB Gene IDBG-14451 (SCARA3)
Protein Structure
UniProt Annotation
Function Seems to protect cells by scavenging oxidative molecules or harmful products of oxidation. {ECO:0000269PubMed:9580669}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000269PubMed:9580669}; Single-pass type II membrane protein {ECO:0000269PubMed:9580669}. Golgi apparatus membrane {ECO:0000269PubMed:9580669}; Single-pass type II membrane protein {ECO:0000269PubMed:9580669}. Note=Endoplasmic reticulum and/or Golgi.
Disease Associations
Tissue Specificity Expressed ubiquitously. {ECO:0000269PubMed:9580669}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005044 scavenger receptor activity
Biological Process
GO:0006898 receptor-mediated endocytosis
GO:0006979 response to oxidative stress
GO:0009650 UV protection
Cellular Component
GO:0000139 Golgi membrane
GO:0005581 collagen trimer
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6AZY7
PhosphoSite PhosphoSite-Q6AZY7
TrEMBL
UniProt Splice Variant
Entrez Gene 51435
UniGene Hs.128856
RefSeq NP_878185
HUGO HGNC:19000
OMIM 602728
CCDS CCDS34870
HPRD 04104
IMGT
EMBL AB007829 AB007830 BC060811 BC075067 BC075068 DQ205185
GenPept AAH60811 AAH75067 AAH75068 ABA27098 BAA86201 BAA86202

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca