Version 5.4
Mus musculus Protein: Cd5
Summary
InnateDB Protein IDBP-144912.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cd5
Protein Name CD5 antigen
Synonyms Ly-1; Ly-12; Ly-A; Lyt-1;
Species Mus musculus
Ensembl Protein ENSMUSP00000025571
InnateDB Gene IDBG-144910 (Cd5)
Protein Structure
UniProt Annotation
Function May act as a receptor in regulating T-cell proliferation.
Subcellular Localization Cell membrane; Single-pass type I membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005044 scavenger receptor activity
GO:0005515 protein binding
Biological Process
GO:0006898 receptor-mediated endocytosis
GO:0031295 T cell costimulation
GO:0097190 apoptotic signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0009897 external side of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:88340
InterPro IPR001190 SRCR domain
IPR003566 T-cell surface glycoprotein CD5
IPR017448 SRCR-like domain
PFAM PF00530
PRINTS PR00258
PR01409
PIRSF
SMART SM00202
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P13379
PhosphoSite PhosphoSite-P13379
TrEMBL Q8C9H0
UniProt Splice Variant
Entrez Gene 12507
UniGene Mm.779
RefSeq NP_031676
MGI ID
MGI Symbol Cd5
OMIM
CCDS CCDS29586
HPRD
IMGT
EMBL AK042105 AK143736 M15177 U09204
GenPept AAA39453 AAC52187 BAC31168 BAE25519

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca