InnateDB Protein
|
IDBP-145547.6
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
Thyn1
|
Protein Name
|
thymocyte nuclear protein 1
|
Synonyms
|
D730042P09Rik; HSPC144; MDS012; MY105; Thy28;
|
Species
|
Mus musculus
|
Ensembl Protein
|
ENSMUSP00000037614
|
InnateDB Gene
|
IDBG-145545 (Thyn1)
|
Protein Structure
|
|
Function |
Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. {ECO:0000269PubMed:23434322}.
|
Subcellular Localization |
Nucleus {ECO:0000269PubMed:14580360, ECO:0000269PubMed:14601557}.
|
Disease Associations |
|
Tissue Specificity |
Expressed in the medulla containing mature thymocytes, but not the cortex having immature thymocytes (at protein level). Abundant expression seen in testis, liver, brain and kidney with lower levels of the expression in thymus, spleen, heart and stomach. {ECO:0000269PubMed:12384300, ECO:0000269PubMed:14580360, ECO:0000269PubMed:14601557}.
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
|
Predicted by orthology |
Total |
5 [view]
|
|
|
Molecular Function |
|
Biological Process |
|
Cellular Component |
|
PDB ID |
MGI:1925112
|
InterPro |
IPR002740
EVE domain
IPR015947
PUA-like domain
|
PFAM |
PF01878
|
PRINTS |
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q91YJ3
|
PhosphoSite |
PhosphoSite-Q91YJ3
|
TrEMBL |
|
UniProt Splice Variant |
|
Entrez Gene |
77862
|
UniGene |
|
RefSeq |
NP_653126
|
MGI ID |
|
MGI Symbol |
Thyn1
|
OMIM |
|
CCDS |
CCDS22937
|
HPRD |
|
IMGT |
|
EMBL |
AB080370
BC016594
|
GenPept |
AAH16594
BAC21100
|
|
|