Version 5.4
Mus musculus Protein: Vps26b
Summary
InnateDB Protein IDBP-145618.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Vps26b
Protein Name vacuolar protein sorting 26 homolog B (yeast)
Synonyms 1810012I05Rik; 2310075A12Rik; AI848392;
Species Mus musculus
Ensembl Protein ENSMUSP00000034470
InnateDB Gene IDBG-145616 (Vps26b)
Protein Structure
UniProt Annotation
Function Probable component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network.
Subcellular Localization Cytoplasm {ECO:0000269PubMed:16190980}. Membrane {ECO:0000269PubMed:16190980}; Peripheral membrane protein {ECO:0000269PubMed:16190980}. Note=Does not localize to endosomes.
Disease Associations
Tissue Specificity Ubiquitously expressed in developing embryo and adult. {ECO:0000269PubMed:16190980}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0015031 protein transport
Cellular Component
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0043231 intracellular membrane-bounded organelle
Protein Structure and Domains
PDB ID MGI:1917656
InterPro IPR014756 Immunoglobulin E-set
IPR028934 Vacuolar protein sorting protein 26 related
PFAM PF03643
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8C0E2
PhosphoSite PhosphoSite-Q8C0E2
TrEMBL
UniProt Splice Variant
Entrez Gene 69091
UniGene Mm.446942
RefSeq NP_821170
MGI ID 3LHA
MGI Symbol Vps26b
OMIM
CCDS CCDS22938
HPRD
IMGT
EMBL AK031589 AK150929 AK155578 AK165539 AK171154 BC029758 BC049180 BC052721 BC062972
GenPept AAH29758 AAH49180 AAH52721 AAH62972 BAC27465 BAE29967 BAE33333 BAE38244 BAE42279

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca