Version 5.4
Mus musculus Protein: Brf2
Summary
InnateDB Protein IDBP-145731.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Brf2
Protein Name BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like
Synonyms 2700059M06Rik; 5730512K07Rik; AU018504; AU022602; BRFU; TFIIIB50;
Species Mus musculus
Ensembl Protein ENSMUSP00000033877
InnateDB Gene IDBG-145729 (Brf2)
Protein Structure
UniProt Annotation
Function General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 55 interaction(s) predicted by orthology.
Predicted by orthology
Total 55 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008270 zinc ion binding
Biological Process
GO:0006352 DNA-templated transcription, initiation
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:1913903
InterPro IPR013137 Zinc finger, TFIIB-type
IPR013763 Cyclin-like
PFAM PF08271
PRINTS
PIRSF
SMART SM00385
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3UAW9
PhosphoSite PhosphoSite-Q3UAW9
TrEMBL
UniProt Splice Variant
Entrez Gene 66653
UniGene Mm.334467
RefSeq NP_079962
MGI ID
MGI Symbol Brf2
OMIM
CCDS CCDS22211
HPRD
IMGT
EMBL AK012680 AK028228 AK151198 BC098232
GenPept AAH98232 BAB28406 BAC25827 BAE30195

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca