InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Camk2b

Summary

InnateDB Protein

IDBP-145824.5

Last Modified

2012-02-14 [Report errors or provide feedback]

Gene Symbol

Camk2b

Protein Name

calcium/calmodulin-dependent protein kinase II, beta

Synonyms

Camk2d;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000087925

InnateDB Gene

IDBG-145820 (Camk2b)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.

Experimentally validated
Total	11 [view]
Protein-Protein	11 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	12 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004683	calmodulin-dependent protein kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005516	calmodulin binding
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0000082	G1/S transition of mitotic cell cycle
GO:0002030	inhibitory G-protein coupled receptor phosphorylation
GO:0006468	protein phosphorylation
GO:0006816	calcium ion transport
GO:0018105	peptidyl-serine phosphorylation
GO:0032222	regulation of synaptic transmission, cholinergic
GO:0046686	response to cadmium ion
GO:0046777	protein autophosphorylation
GO:0048169	regulation of long-term neuronal synaptic plasticity
GO:0050885	neuromuscular process controlling balance
GO:0060466	activation of meiosis involved in egg activation
GO:2001235	positive regulation of apoptotic signaling pathway

Cellular Component

GO:0005829	cytosol
GO:0005954	calcium- and calmodulin-dependent protein kinase complex
GO:0051233	spindle midzone

Protein Structure and Domains

PDB ID

MGI:88257

InterPro

IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine- /dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR013543 Calcium/calmodulin-dependent protein kinase II, association-domain
IPR020635 Tyrosine-protein kinase, catalytic domain

PFAM

PF00069
PF07714
PF08332

PRINTS

PR00109

PIRSF

SMART

SM00220
SM00219

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt