Version 5.4
Mus musculus Protein: Lipt1
Summary
InnateDB Protein IDBP-146393.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lipt1
Protein Name lipoyltransferase 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000038739
InnateDB Gene IDBG-146391 (Lipt1)
Protein Structure
UniProt Annotation
Function Catalyzes the transfer of the lipoyl group from lipoyl- AMP to the specific lysine residue of lipoyl domains of lipoate- dependent enzymes. {ECO:0000250}.
Subcellular Localization Mitochondrion {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0016740 transferase activity
GO:0016746 transferase activity, transferring acyl groups
Biological Process
GO:0006464 cellular protein modification process
GO:0008150 biological_process
GO:0009249 protein lipoylation
Cellular Component
GO:0005739 mitochondrion
Protein Structure and Domains
PDB ID MGI:3645211
InterPro IPR004143 Biotin/lipoate A/B protein ligase
IPR004562 Lipoyltransferase/lipoate-protein ligase
PFAM PF03099
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8VCM4
PhosphoSite PhosphoSite-Q8VCM4
TrEMBL D3Z7N1
UniProt Splice Variant
Entrez Gene 623661
UniGene Mm.389100
RefSeq NP_001033007
MGI ID
MGI Symbol Lipt1
OMIM
CCDS CCDS14895
HPRD
IMGT
EMBL AC119189 BC019519
GenPept AAH19519

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca