InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Hdhd1a

Summary

InnateDB Protein

IDBP-146497.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Hdhd1a

Protein Name

haloacid dehalogenase-like hydrolase domain containing 1A

Synonyms

1700121L12Rik; GS1; Hdhd1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000057378

InnateDB Gene

IDBG-146495 (Hdhd1a)

Protein Structure

UniProt Annotation

Function

Dephosphorylates pseudouridine 5'-phosphate, a potential intermediate in rRNA degradation. Pseudouridine is then excreted intact in urine (By similarity). {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0016787	hydrolase activity
GO:0016791	phosphatase activity
GO:0046872	metal ion binding

Biological Process

GO:0008150	biological_process
GO:0008152	metabolic process
GO:0009117	nucleotide metabolic process
GO:0016311	dephosphorylation

Cellular Component

GO:0005575	cellular_component
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:1914615

InterPro

IPR006439 HAD hydrolase, subfamily IA
IPR023214 HAD-like domain

PFAM

PF00702
PF08282
PF13419

PRINTS

PR00413

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9D5U5

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

67365

UniGene

Mm.158150

RefSeq

NP_080384

MGI ID

MGI Symbol

Hdhd1a

OMIM

CCDS

CCDS29244

HPRD

IMGT

EMBL

AK007231 AK014922 BC048447

GenPept

AAH48447 BAB24906 BAB29622