InnateDB Protein
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IDBP-146788.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Mmgt1
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Protein Name
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membrane magnesium transporter 1
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000051621
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InnateDB Gene
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IDBG-146786 (Mmgt1)
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Protein Structure
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Function |
Mediates Mg(2+) transport. {ECO:0000269PubMed:18057121}.
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Subcellular Localization |
Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Golgi apparatus membrane {ECO:0000269PubMed:18057121}; Single- pass type I membrane protein {ECO:0000269PubMed:18057121}. Early endosome membrane {ECO:0000269PubMed:18057121}; Single-pass type I membrane protein {ECO:0000269PubMed:18057121}. Note=Detected in the Golgi apparatus and in post-Golgi vesicles including early endosomes.
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Disease Associations |
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Tissue Specificity |
Abundant in heart muscle and kidney with lower levels in liver and brain and very little expression in intestine or colon. In kidney, highest levels in distal convoluted tubule. {ECO:0000269PubMed:18057121}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Experimentally validated |
Total |
1
[view]
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Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
14 [view]
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Molecular Function |
Accession |
GO Term |
GO:0015087
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cobalt ion transmembrane transporter activity
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GO:0015093
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ferrous iron transmembrane transporter activity
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GO:0015095
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magnesium ion transmembrane transporter activity
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GO:0022890
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inorganic cation transmembrane transporter activity
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:2384305
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InterPro |
IPR018937
Magnesium transporter
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PFAM |
PF10270
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8K273
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PhosphoSite |
PhosphoSite-Q8K273
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
236792
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UniGene |
Mm.474780
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RefSeq |
NP_666346
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MGI ID |
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MGI Symbol |
Mmgt1
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OMIM |
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CCDS |
CCDS30147
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HPRD |
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IMGT |
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EMBL |
AK036253
AK043524
AK049689
BC032271
EU069461
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GenPept |
AAH32271
ABS87351
BAC29362
BAC31567
BAC33874
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