Version 5.4
Mus musculus Protein: Strn4
Summary
InnateDB Protein IDBP-146949.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Strn4
Protein Name striatin, calmodulin binding protein 4
Synonyms C80611; ZIN; zinedin;
Species Mus musculus
Ensembl Protein ENSMUSP00000019220
InnateDB Gene IDBG-146947 (Strn4)
Protein Structure
UniProt Annotation
Function Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein.
Subcellular Localization Cytoplasm. Membrane; Peripheral membrane protein. Cell projection, dendritic spine {ECO:0000250}. Note=CTTNBP2-binding may regulate dendritic spine distribution. {ECO:0000250}.
Disease Associations
Tissue Specificity Mainly expressed in brain but is also expressed at low levels in the kidney.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 61 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 61 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005516 calmodulin binding
GO:0019904 protein domain specific binding
GO:0032403 protein complex binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005737 cytoplasm
GO:0016020 membrane
GO:0043197 dendritic spine
GO:0043234 protein complex
Protein Structure and Domains
PDB ID MGI:2142346
InterPro IPR001680 WD40 repeat
IPR013258 Striatin, N-terminal
IPR017986 WD40-repeat-containing domain
IPR020472 G-protein beta WD-40 repeat
PFAM PF00400
PF08232
PRINTS PR00320
PIRSF
SMART SM00320
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P58404
PhosphoSite PhosphoSite-P58404
TrEMBL V9GX64
UniProt Splice Variant
Entrez Gene 97387
UniGene Mm.21612
RefSeq NP_598550
MGI ID
MGI Symbol Strn4
OMIM
CCDS CCDS39786
HPRD
IMGT
EMBL AC148981 AF414080 BC004025 BC080283
GenPept AAH04025 AAH80283 AAL07439

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca