InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Sec63

Summary

InnateDB Protein

IDBP-147684.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Sec63

Protein Name

SEC63-like (S. cerevisiae)

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000019937

InnateDB Gene

IDBG-147682 (Sec63)

Protein Structure

UniProt Annotation

Function

Required for integral membrane and secreted preprotein translocation across the endoplasmic reticulum membrane. {ECO:0000250}.

Subcellular Localization

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005488	binding
GO:0005515	protein binding
GO:0008565	protein transporter activity
GO:0044822	poly(A) RNA binding

Biological Process

GO:0001889	liver development
GO:0006614	SRP-dependent cotranslational protein targeting to membrane
GO:0006620	posttranslational protein targeting to membrane
GO:0006807	nitrogen compound metabolic process
GO:0010259	multicellular organismal aging
GO:0031204	posttranslational protein targeting to membrane, translocation
GO:0072001	renal system development