InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ubac1

Summary

InnateDB Protein

IDBP-147715.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ubac1

Protein Name

ubiquitin associated domain containing 1

Synonyms

1110033G07Rik; AA407978; GBDR1; Gdbr1; Ubadc1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000040220

InnateDB Gene

IDBG-147713 (Ubac1)

Protein Structure

UniProt Annotation

Function

Non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle (By similarity). {ECO:0000250}.

Subcellular Localization

Cytoplasm {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 29 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	29 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding

Biological Process

GO:0008150	biological_process
GO:0016567	protein ubiquitination

Cellular Component

GO:0005737	cytoplasm
GO:0005794	Golgi apparatus
GO:0005886	plasma membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:1920995

InterPro

IPR000449 Ubiquitin-associated domain/translation elongation factor EF-Ts, N-terminal
IPR006636 Heat shock chaperonin-binding
IPR009060 UBA-like
IPR015940 Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote
IPR029071 Ubiquitin-related domain

PFAM

PF00627

PRINTS

PIRSF

SMART

SM00727
SM00165

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8VDI7