InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Psat1

Summary

InnateDB Protein

IDBP-149657.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Psat1

Protein Name

phosphoserine aminotransferase 1

Synonyms

D8Ertd814e; EPIP; PSA; Psat;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000025542

InnateDB Gene

IDBG-149655 (Psat1)

Protein Structure

UniProt Annotation

Function

Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	21 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004648	O-phospho-L-serine:2-oxoglutarate aminotransferase activity
GO:0030170	pyridoxal phosphate binding

Biological Process

GO:0006564	L-serine biosynthetic process
GO:0008152	metabolic process

Cellular Component

GO:0070062

extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:2183441

InterPro

IPR000192 Aminotransferase, class V/Cysteine desulfurase
IPR003248 Phosphoserine aminotransferase, subgroup
IPR015424 Pyridoxal phosphate-dependent transferase
IPR022278 Phosphoserine aminotransferase

PFAM

PF00266

PRINTS

PIRSF

PIRSF000525

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q99K85