InnateDB Protein
|
IDBP-149881.6
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
Vps37a
|
Protein Name
|
vacuolar protein sorting 37A (yeast)
|
Synonyms
|
2210018P21Rik; 4930592A21Rik; AW261445; D8Ertd531e;
|
Species
|
Mus musculus
|
Ensembl Protein
|
ENSMUSP00000096415
|
InnateDB Gene
|
IDBG-149879 (Vps37a)
|
Protein Structure
|
|
Function |
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation (By similarity). {ECO:0000250}.
|
Subcellular Localization |
Late endosome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Nucleus {ECO:0000250}.
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
|
Predicted by orthology |
Total |
10 [view]
|
|
|
Molecular Function |
|
Biological Process |
GO:0015031
|
protein transport
|
GO:0043162
|
ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
|
|
Cellular Component |
|
PDB ID |
MGI:1261835
|
InterPro |
IPR009851
Modifier of rudimentary, Modr
IPR016135
Ubiquitin-conjugating enzyme/RWD-like
|
PFAM |
PF07200
|
PRINTS |
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q8CHS8
|
PhosphoSite |
PhosphoSite-Q8CHS8
|
TrEMBL |
|
UniProt Splice Variant |
|
Entrez Gene |
52348
|
UniGene |
Mm.489696
|
RefSeq |
NP_291038
|
MGI ID |
|
MGI Symbol |
Vps37a
|
OMIM |
|
CCDS |
CCDS22254
|
HPRD |
|
IMGT |
|
EMBL |
AK170943
AK170961
AK171055
AK171221
BC039290
BC110396
|
GenPept |
AAH39290
AAI10397
BAE42131
BAE42142
BAE42215
BAE42324
|
|
|