Version 5.4
| Mus musculus Protein: Neurod6 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-150369.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Neurod6 | ||||||||
| Protein Name | neurogenic differentiation 6 | ||||||||
| Synonyms | Atoh2; bHLHa2; Math-2; Math2; Nex; Nex1m; | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000047016 | ||||||||
| InnateDB Gene | IDBG-150367 (Neurod6) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Activates E box-dependent transcription in collaboration with TCF3/E47. May be a trans-acting factor involved in the development and maintenance of the mammalian nervous system. Transactivates the promoter of its own gene. | ||||||||
| Subcellular Localization | Nucleus {ECO:0000305}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Specific to the nervous system of both embryos and adults. Highest levels in the cortical plate of the cerebrum. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:106593 | ||||||||
| InterPro |
IPR011598
Myc-type, basic helix-loop-helix (bHLH) domain IPR016637 Transcription factor, basic helix-loop-helix, NeuroD IPR022575 Neurogenic differentiation factor, domain of unknown function |
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| PFAM |
PF00010
PF12533 |
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| PRINTS | |||||||||
| PIRSF |
PIRSF015618
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| SMART |
SM00353
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | P48986 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | Q5M8T7 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 11922 | ||||||||
| UniGene | Mm.5106 | ||||||||
| RefSeq | NP_033847 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Neurod6 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS20168 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | BC087831 CH466597 D44480 U29086 | ||||||||
| GenPept | AAC14576 AAH87831 BAA07923 EDK98732 | ||||||||