InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Vgll2

Summary

InnateDB Protein

IDBP-150564.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Vgll2

Protein Name

vestigial like 2 homolog (Drosophila)

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000050273

InnateDB Gene

IDBG-150562 (Vgll2)

Protein Structure

UniProt Annotation

Function

May act as a specific coactivator for the mammalian TEFs. May play a role in the development of skeletal muscles. {ECO:0000269PubMed:12376544}.

Subcellular Localization

Nucleus {ECO:0000269PubMed:12376544}.

Disease Associations

Tissue Specificity

Skeletal muscle specific. {ECO:0000269PubMed:12617818}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003713	transcription coactivator activity
GO:0005515	protein binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0007519	skeletal muscle tissue development
GO:0045944	positive regulation of transcription from RNA polymerase II promoter

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

MGI:2447460

InterPro

IPR011520 Vestigial/tondu

PFAM

PF07545

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8BGW8

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

215031

UniGene

Mm.87237

RefSeq

MGI ID

MGI Symbol

Vgll2

OMIM

CCDS

HPRD

IMGT

EMBL

AF542181 AJ578054 AK048390 AK052987

GenPept

AAN37898 BAC33319 BAC35232 CAE17332