InnateDB Protein
|
IDBP-150646.6
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
Ckm
|
Protein Name
|
creatine kinase, muscle
|
Synonyms
|
Ckmm; M-CK; MCK;
|
Species
|
Mus musculus
|
Ensembl Protein
|
ENSMUSP00000003643
|
InnateDB Gene
|
IDBG-150644 (Ckm)
|
Protein Structure
|
|
Function |
Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
|
Subcellular Localization |
Cytoplasm.
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated |
Total |
14
[view]
|
Protein-Protein |
10
[view]
|
Protein-DNA |
4
[view]
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
Predicted by orthology |
Total |
7 [view]
|
|
|
Molecular Function |
|
Biological Process |
|
Cellular Component |
|
PDB ID |
MGI:88413
|
InterPro |
IPR022413
ATP:guanido phosphotransferase, N-terminal
IPR022414
ATP:guanido phosphotransferase, catalytic domain
|
PFAM |
PF02807
PF00217
|
PRINTS |
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
P07310
|
PhosphoSite |
PhosphoSite-P07310
|
TrEMBL |
A2RTA0
|
UniProt Splice Variant |
|
Entrez Gene |
12715
|
UniGene |
Mm.2375
|
RefSeq |
NP_031736
|
MGI ID |
|
MGI Symbol |
Ckm
|
OMIM |
|
CCDS |
CCDS20902
|
HPRD |
|
IMGT |
|
EMBL |
BC132424
BC132426
CH466639
X03233
|
GenPept |
AAI32425
AAI32427
CAA26979
EDL23143
|
|
|