Version 5.4
Mus musculus Protein: Ostf1
Summary
InnateDB Protein IDBP-151165.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ostf1
Protein Name osteoclast stimulating factor 1
Synonyms C78236; Sh3d3; SH3P2;
Species Mus musculus
Ensembl Protein ENSMUSP00000025631
InnateDB Gene IDBG-151163 (Ostf1)
Protein Structure
UniProt Annotation
Function Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0017124 SH3 domain binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:700012
InterPro IPR001452 SH3 domain
IPR002110 Ankyrin repeat
IPR011511 Variant SH3 domain
IPR020683 Ankyrin repeat-containing domain
PFAM PF00018
PF14604
PF00023
PF13606
PF07653
PF11929
PF12796
PRINTS PR00452
PR01415
PIRSF
SMART SM00326
SM00248
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q62422
PhosphoSite PhosphoSite-Q62422
TrEMBL
UniProt Splice Variant
Entrez Gene 20409
UniGene Mm.392529
RefSeq NP_059071
MGI ID
MGI Symbol Ostf1
OMIM
CCDS CCDS37930
HPRD
IMGT
EMBL AK002899 AK005525 AK008123 AK008467 AK010074 AK145949 AK149175 AK150145 AK155028 BC060986 U58888
GenPept AAC52641 AAH60986 BAB22442 BAB24098 BAB25477 BAB25685 BAB26683 BAE26777 BAE28756 BAE29340 BAE33000

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca