Version 5.4
Mus musculus Protein: Cel
Summary
InnateDB Protein IDBP-152329.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cel
Protein Name carboxyl ester lipase
Synonyms 1810036E18Rik; BAL;
Species Mus musculus
Ensembl Protein ENSMUSP00000028161
InnateDB Gene IDBG-152327 (Cel)
Protein Structure
UniProt Annotation
Function Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides (By similarity). {ECO:0000250}.
Subcellular Localization Secreted {ECO:0000250}.
Disease Associations
Tissue Specificity EXpressed by eosinophils. {ECO:0000269PubMed:11834744}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004771 sterol esterase activity
GO:0004806 triglyceride lipase activity
GO:0005515 protein binding
GO:0016787 hydrolase activity
GO:0047372 acylglycerol lipase activity
GO:0052689 carboxylic ester hydrolase activity
Biological Process
GO:0006707 cholesterol catabolic process
GO:0008152 metabolic process
GO:0030157 pancreatic juice secretion
GO:0046514 ceramide catabolic process
Cellular Component
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:88374
InterPro IPR002018 Carboxylesterase, type B
IPR013094 Alpha/beta hydrolase fold-3
IPR029058 Alpha/Beta hydrolase fold
PFAM PF00135
PF07859
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q64285
PhosphoSite PhosphoSite-
TrEMBL Q3V2H7
UniProt Splice Variant
Entrez Gene 12613
UniGene Mm.236017
RefSeq NP_034015
MGI ID
MGI Symbol Cel
OMIM
CCDS CCDS15841
HPRD
IMGT
EMBL AK131818 AK131824 CH466542 U33169 U37386
GenPept AAA92088 AAC52279 BAE20818 BAE20820 EDL08386

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca