Version 5.4
Mus musculus Protein: Gtf3c5
Summary
InnateDB Protein IDBP-152443.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gtf3c5
Protein Name general transcription factor IIIC, polypeptide 5
Synonyms 2700084A09Rik; TFiiiC2-63; TFIIIC63;
Species Mus musculus
Ensembl Protein ENSMUSP00000028157
InnateDB Gene IDBG-152441 (Gtf3c5)
Protein Structure
UniProt Annotation
Function Involved in RNA polymerase III-mediated transcription. Integral, tightly associated component of the DNA-binding TFIIIC2 subcomplex that directly binds tRNA and virus-associated RNA promoters (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 24 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003677 DNA binding
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0035914 skeletal muscle cell differentiation
Cellular Component
GO:0000127 transcription factor TFIIIC complex
Protein Structure and Domains
PDB ID MGI:1917489
InterPro IPR019136 Transcription factor IIIC, subunit 5
PFAM PF09734
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8R2T8
PhosphoSite PhosphoSite-Q8R2T8
TrEMBL Q3UI98
UniProt Splice Variant
Entrez Gene 70239
UniGene Mm.274120
RefSeq NP_683730
MGI ID
MGI Symbol Gtf3c5
OMIM
CCDS CCDS15842
HPRD
IMGT
EMBL AK045419 AK147014 BC027055 BC027247 BC039171 CH466542
GenPept AAH27055 AAH27247 AAH39171 BAC32354 BAE27608 EDL08389

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca