InnateDB Protein
|
IDBP-152710.6
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
Fkbp15
|
Protein Name
|
FK506 binding protein 15
|
Synonyms
|
|
Species
|
Mus musculus
|
Ensembl Protein
|
ENSMUSP00000081575
|
InnateDB Gene
|
IDBG-152708 (Fkbp15)
|
Protein Structure
|
|
Function |
Involved in the transport of early endosomes at the level of transition between microfilament-based and microtubule- based movement (By similarity). May be involved in the cytoskeletal organization of neuronal growth cones. Seems to be inactive as a PPIase. {ECO:0000250, ECO:0000269PubMed:16756961}.
|
Subcellular Localization |
Cytoplasm {ECO:0000269PubMed:16756961}. Cell projection, axon {ECO:0000269PubMed:16756961}. Early endosome {ECO:0000269PubMed:16756961}. Note=Present in axons and neuronal growth cones.
|
Disease Associations |
|
Tissue Specificity |
Expressed in brain, with highest levels in the granular cell layer of cerebellum and in the granule cell layer of dentate gyrus. {ECO:0000269PubMed:16756961}.
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated |
Total |
1
[view]
|
Protein-Protein |
1
[view]
|
Protein-DNA |
0
|
Protein-RNA |
0
|
DNA-DNA |
0
|
RNA-RNA |
0
|
DNA-RNA |
0
|
|
Predicted by orthology |
Total |
5 [view]
|
|
|
Molecular Function |
|
Biological Process |
|
Cellular Component |
|
PDB ID |
MGI:2444782
|
InterPro |
IPR001179
Peptidyl-prolyl cis-trans isomerase, FKBP-type, domain
|
PFAM |
PF00254
|
PRINTS |
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q6P9Q6
|
PhosphoSite |
PhosphoSite-Q6P9Q6
|
TrEMBL |
B2RQ18
|
UniProt Splice Variant |
|
Entrez Gene |
338355
|
UniGene |
|
RefSeq |
NP_001038993
|
MGI ID |
|
MGI Symbol |
Fkbp15
|
OMIM |
|
CCDS |
CCDS51201
|
HPRD |
|
IMGT |
|
EMBL |
AK122343
AK161705
AL683829
AL732548
BC060651
BC137706
|
GenPept |
AAH60651
AAI37707
BAC65625
BAE36541
CAI25942
CAI26145
|
|
|