InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Slc31a1

Summary

InnateDB Protein

IDBP-153023.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Slc31a1

Protein Name

solute carrier family 31, member 1

Synonyms

4930445G01Rik; AI787263; AU016967; Ctr1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000081574

InnateDB Gene

IDBG-153021 (Slc31a1)

Protein Structure

UniProt Annotation

Function

High-affinity, saturable copper transporter involved in dietary copper uptake. {ECO:0000269PubMed:20699218}.

Subcellular Localization

Cell membrane {ECO:0000269PubMed:20699218}; Multi-pass membrane protein {ECO:0000269PubMed:20699218}. Note=Localizes to the apical membrane in intestinal epithelial cells.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005375	copper ion transmembrane transporter activity
GO:0005515	protein binding
GO:0015088	copper uptake transmembrane transporter activity

Biological Process

GO:0006855	drug transmembrane transport
GO:0006878	cellular copper ion homeostasis
GO:0015677	copper ion import
GO:0035434	copper ion transmembrane transport
GO:0072719	cellular response to cisplatin
GO:1902861	copper ion import into cell

Cellular Component

GO:0005737	cytoplasm
GO:0005770	late endosome
GO:0005886	plasma membrane
GO:0016021	integral component of membrane
GO:0043025	neuronal cell body
GO:0055037	recycling endosome