InnateDB Protein
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IDBP-153763.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Hibch
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Protein Name
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3-hydroxyisobutyryl-Coenzyme A hydrolase
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000045606
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InnateDB Gene
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IDBG-153761 (Hibch)
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Protein Structure
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Function |
Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA (By similarity). {ECO:0000250}.
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Subcellular Localization |
Mitochondrion {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated |
Total |
4
[view]
|
Protein-Protein |
4
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
4 [view]
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Molecular Function |
Accession |
GO Term |
GO:0003824
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catalytic activity
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GO:0003860
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3-hydroxyisobutyryl-CoA hydrolase activity
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1923792
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InterPro |
IPR001753
Crotonase superfamily
IPR029045
ClpP/crotonase-like domain
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PFAM |
PF00378
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8QZS1
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PhosphoSite |
PhosphoSite-Q8QZS1
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
227095
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UniGene |
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RefSeq |
NP_666220
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MGI ID |
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MGI Symbol |
Hibch
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OMIM |
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CCDS |
CCDS14948
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HPRD |
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IMGT |
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EMBL |
AK076038
BC026437
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GenPept |
AAH26437
BAC36138
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