InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: BET1L

Summary

InnateDB Protein

IDBP-15441.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BET1L

Protein Name

blocked early in transport 1 homolog (S. cerevisiae)-like

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000372210

InnateDB Gene

IDBG-15437 (BET1L)

Protein Structure

UniProt Annotation

Function

Vesicle SNARE required for targeting and fusion of retrograde transport vesicles with the Golgi complex. Required for the integrity of the Golgi complex (By similarity). {ECO:0000250UniProtKB:O35152}.

Subcellular Localization

Golgi apparatus membrane {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}. Golgi apparatus, trans-Golgi network membrane {ECO:0000250}. Note=Present throughout the Golgi apparatus, with increasing concentration from cis-Golgi to the trans-Golgi face of the stacks. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.

Experimentally validated
Total	9 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005484	SNAP receptor activity
GO:0005515	protein binding

Biological Process

GO:0015031	protein transport
GO:0042147	retrograde transport, endosome to Golgi

Cellular Component

GO:0000139	Golgi membrane
GO:0005768	endosome
GO:0005794	Golgi apparatus
GO:0005795	Golgi stack
GO:0016020	membrane
GO:0030173	integral component of Golgi membrane
GO:0031201	SNARE complex