InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CCM2

Summary

InnateDB Protein

IDBP-15470.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CCM2

Protein Name

cerebral cavernous malformation 2

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000370503

InnateDB Gene

IDBG-15466 (CCM2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	10 [view]
Protein-Protein	10 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0001568	blood vessel development
GO:0001570	vasculogenesis
GO:0001701	in utero embryonic development
GO:0001885	endothelial cell development
GO:0001944	vasculature development
GO:0007229	integrin-mediated signaling pathway
GO:0007507	heart development
GO:0035264	multicellular organism growth
GO:0045216	cell-cell junction organization
GO:0048839	inner ear development
GO:0048845	venous blood vessel morphogenesis
GO:0051403	stress-activated MAPK cascade
GO:0060039	pericardium development
GO:0060837	blood vessel endothelial cell differentiation
GO:0061154	endothelial tube morphogenesis