InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Pgm5

Summary

InnateDB Protein

IDBP-154726.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Pgm5

Protein Name

phosphoglucomutase 5

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000036025

InnateDB Gene

IDBG-154724 (Pgm5)

Protein Structure

UniProt Annotation

Function

Component of adherens-type cell-cell and cell-matrix junctions. Lacks phosphoglucomutase activity (By similarity). {ECO:0000250}.

Subcellular Localization

Cell junction, adherens junction. Cytoplasm, cytoskeleton. Note=Adherens-type cellular junctions. Concentrated in focal contacts at the ends of actin bundles, and associated with actin filaments (By similarity). {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000287	magnesium ion binding
GO:0005515	protein binding
GO:0016868	intramolecular transferase activity, phosphotransferases

Biological Process

GO:0005975	carbohydrate metabolic process
GO:0006006	glucose metabolic process
GO:0007155	cell adhesion

Cellular Component

GO:0001725	stress fiber
GO:0005913	cell-cell adherens junction
GO:0005914	spot adherens junction
GO:0005925	focal adhesion
GO:0009898	cytoplasmic side of plasma membrane
GO:0014704	intercalated disc
GO:0016010	dystrophin-associated glycoprotein complex
GO:0030018	Z disc
GO:0030055	cell-substrate junction
GO:0042383	sarcolemma
GO:0043034	costamere

Protein Structure and Domains

PDB ID

MGI:1925668

InterPro

IPR005841 Alpha-D-phosphohexomutase superfamily
IPR005843 Alpha-D-phosphohexomutase, C-terminal
IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I
IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II
IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III
IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III

PFAM

PF00408
PF02878
PF02879
PF02880

PRINTS

PR00509

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8BZF8