Version 5.4
Mus musculus Protein: Mars2
Summary
InnateDB Protein IDBP-155421.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mars2
Protein Name methionine-tRNA synthetase 2 (mitochondrial)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000049770
InnateDB Gene IDBG-155419 (Mars2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Mitochondrion matrix {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004825 methionine-tRNA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0006418 tRNA aminoacylation for protein translation
GO:0006431 methionyl-tRNA aminoacylation
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
Protein Structure and Domains
PDB ID MGI:2444136
InterPro IPR002300 Aminoacyl-tRNA synthetase, class Ia
IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding
IPR014758 Methionyl-tRNA synthetase
IPR015413 Methionyl/Leucyl tRNA synthetase
IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase
PFAM PF00133
PF09334
PF01406
PRINTS PR01041
PR00983
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q499X9
PhosphoSite PhosphoSite-Q499X9
TrEMBL A2RT28
UniProt Splice Variant
Entrez Gene 212679
UniGene Mm.19223
RefSeq NP_780648
MGI ID
MGI Symbol Mars2
OMIM
CCDS CCDS14963
HPRD
IMGT
EMBL AK042888 AK050196 AK172240 BC099669 BC132343 BC137739 CH466548
GenPept AAH99669 AAI32344 AAI37740 BAC31393 BAC34119 BAE42903 EDL00030

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca