Mus musculus Protein: Cd8b1
Summary
InnateDB Protein IDBP-155549.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cd8b1
Protein Name CD8 antigen, beta chain 1
Synonyms Cd8b; Ly-3; Ly-C; Lyt-3;
Species Mus musculus
Ensembl Protein ENSMUSP00000070131
InnateDB Gene IDBG-155547 (Cd8b1)
Protein Structure
UniProt Annotation
Function Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing.
Subcellular Localization Membrane; Single-pass type I membrane protein.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0002376 immune system process
Cellular Component
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:88347
InterPro IPR003596 Immunoglobulin V-set, subgroup
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR013106 Immunoglobulin V-set domain
PFAM PF07686
PRINTS
PIRSF
SMART SM00406
SM00409
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P10300
PhosphoSite PhosphoSite-P10300
TrEMBL Q3TEK8
UniProt Splice Variant
Entrez Gene 12526
UniGene Mm.412492
RefSeq NP_033988
MGI ID 3DMM
MGI Symbol Cd8b1
OMIM
CCDS CCDS39506
HPRD
IMGT
EMBL AK169581 CH466523 M16799 M17534 M19504 M22065 M22066 M22067 M22068 M22069 M22070 M26441 M26442 M26443 M26444 M26445 M26446 U34882 X07698 X07997
GenPept AAA39454 AAA39455 AAA39456 AAA39479 AAA39480 AAA92534 BAE41240 CAA30537 CAA30803 EDK98935