InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Htt

Summary

InnateDB Protein

IDBP-156035.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Htt

Protein Name

huntingtin

Synonyms

AI256365; C430023I11Rik; Hd; Hdh; IT15;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000078945

InnateDB Gene

IDBG-156033 (Htt)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 187 experimentally validated interaction(s) in this database.
They are also associated with 131 interaction(s) predicted by orthology.

Experimentally validated
Total	187 [view]
Protein-Protein	184 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	131 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0002039	p53 binding
GO:0005488	binding
GO:0005515	protein binding
GO:0008134	transcription factor binding
GO:0034452	dynactin binding
GO:0042802	identical protein binding
GO:0045505	dynein intermediate chain binding
GO:0048487	beta-tubulin binding
GO:0050809	diazepam binding

Biological Process

GO:0000050	urea cycle
GO:0000052	citrulline metabolic process
GO:0000132	establishment of mitotic spindle orientation
GO:0006606	protein import into nucleus
GO:0006839	mitochondrial transport
GO:0006888	ER to Golgi vesicle-mediated transport
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER
GO:0006915	apoptotic process
GO:0007005	mitochondrion organization
GO:0007029	endoplasmic reticulum organization
GO:0007030	Golgi organization
GO:0007212	dopamine receptor signaling pathway
GO:0007283	spermatogenesis
GO:0007369	gastrulation
GO:0007417	central nervous system development
GO:0007420	brain development
GO:0007569	cell aging
GO:0007611	learning or memory
GO:0007612	learning
GO:0007625	grooming behavior
GO:0007626	locomotory behavior
GO:0008088	axon cargo transport
GO:0008306	associative learning
GO:0008340	determination of adult lifespan
GO:0008542	visual learning
GO:0009653	anatomical structure morphogenesis
GO:0009952	anterior/posterior pattern specification
GO:0016197	endosomal transport
GO:0019244	lactate biosynthetic process from pyruvate
GO:0019805	quinolinate biosynthetic process
GO:0021756	striatum development
GO:0021988	olfactory lobe development
GO:0021990	neural plate formation
GO:0022008	neurogenesis
GO:0030072	peptide hormone secretion
GO:0030073	insulin secretion
GO:0034047	regulation of protein phosphatase type 2A activity
GO:0035176	social behavior
GO:0042445	hormone metabolic process
GO:0043066	negative regulation of apoptotic process
GO:0043524	negative regulation of neuron apoptotic process
GO:0046825	regulation of protein export from nucleus
GO:0046902	regulation of mitochondrial membrane permeability
GO:0047496	vesicle transport along microtubule
GO:0048167	regulation of synaptic plasticity
GO:0048341	paraxial mesoderm formation
GO:0048666	neuron development
GO:0051402	neuron apoptotic process
GO:0051592	response to calcium ion
GO:0051881	regulation of mitochondrial membrane potential
GO:0051938	L-glutamate import
GO:0055072	iron ion homeostasis
GO:1901215	negative regulation of neuron death
GO:2001237	negative regulation of extrinsic apoptotic signaling pathway

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005770	late endosome
GO:0005776	autophagic vacuole
GO:0005783	endoplasmic reticulum
GO:0005794	Golgi apparatus
GO:0005829	cytosol
GO:0016023	cytoplasmic membrane-bounded vesicle
GO:0016234	inclusion body
GO:0030424	axon
GO:0030425	dendrite
GO:0030659	cytoplasmic vesicle membrane
GO:0043234	protein complex