Version 5.4
Mus musculus Protein: Reg1
Summary
InnateDB Protein IDBP-158651.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Reg1
Protein Name regenerating islet-derived 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000078847
InnateDB Gene IDBG-158649 (Reg1)
Protein Structure
UniProt Annotation
Function Might act as an inhibitor of spontaneous calcium carbonate precipitation.
Subcellular Localization Secreted {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed only in regenerating islets and normal exocrine pancreas, but not in normal pancreatic islets. Expressed strongly in pancreas, moderately in gall bladder, and weakly in liver.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008083 growth factor activity
GO:0030246 carbohydrate binding
Biological Process
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID MGI:97895
InterPro IPR001304 C-type lectin
IPR002353 Type-2 ice-structuring protein
IPR016187 C-type lectin fold
PFAM PF00059
PRINTS PR00356
PIRSF
SMART SM00034
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P43137
PhosphoSite PhosphoSite-P43137
TrEMBL Q8C6F9
UniProt Splice Variant
Entrez Gene 19692
UniGene Mm.142731
RefSeq NP_033068
MGI ID
MGI Symbol Reg1
OMIM
CCDS CCDS20257
HPRD
IMGT
EMBL AK075798 AK133506 AK160452 BC028761 CH466523 D14010
GenPept AAH28761 BAA03111 BAC35967 BAE21692 BAE35794 EDK99019

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca