Version 5.4
Mus musculus Protein: Elfn2
Summary
InnateDB Protein IDBP-159707.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Elfn2
Protein Name leucine rich repeat and fibronectin type III, extracellular 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000085960
InnateDB Gene IDBG-159705 (Elfn2)
Protein Structure
UniProt Annotation
Function Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes. {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004864 protein phosphatase inhibitor activity
GO:0005515 protein binding
GO:0019902 phosphatase binding
Biological Process
GO:0010923 negative regulation of phosphatase activity
Cellular Component
GO:0005615 extracellular space
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:3608416
InterPro IPR003591 Leucine-rich repeat, typical subtype
IPR003961 Fibronectin, type III
IPR019931 LPXTG cell wall anchor domain
PFAM PF00041
PF01108
PRINTS
PIRSF
SMART SM00369
SM00060
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q68FM6
PhosphoSite PhosphoSite-Q68FM6
TrEMBL
UniProt Splice Variant
Entrez Gene 207393
UniGene Mm.323188
RefSeq NP_898964
MGI ID
MGI Symbol Elfn2
OMIM
CCDS CCDS27621
HPRD
IMGT
EMBL AK031970 AK173294 BC079588 BC094219
GenPept AAH79588 AAH94219 BAC27630 BAD32572

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca