Version 5.4
Mus musculus Protein: Pcyt1b
Summary
InnateDB Protein IDBP-159777.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pcyt1b
Protein Name phosphate cytidylyltransferase 1, choline, beta isoform
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000044280
InnateDB Gene IDBG-159775 (Pcyt1b)
Protein Structure
UniProt Annotation
Function Controls phosphatidylcholine synthesis. {ECO:0000269PubMed:12842190, ECO:0000269PubMed:15143167}.
Subcellular Localization Endoplasmic reticulum {ECO:0000250}.
Disease Associations
Tissue Specificity Highly expressed in brain (at protein level). Expressed at lower levels in lung and gonads. {ECO:0000269PubMed:12842190, ECO:0000269PubMed:15143167}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004105 choline-phosphate cytidylyltransferase activity
Biological Process
GO:0001541 ovarian follicle development
GO:0006657 CDP-choline pathway
GO:0007283 spermatogenesis
GO:0009058 biosynthetic process
Cellular Component
GO:0005783 endoplasmic reticulum
Protein Structure and Domains
PDB ID MGI:2147987
InterPro IPR004821 Cytidyltransferase-like domain
PFAM PF01467
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q811Q9
PhosphoSite PhosphoSite-Q811Q9
TrEMBL
UniProt Splice Variant
Entrez Gene 236899
UniGene Mm.166467
RefSeq NP_997593
MGI ID
MGI Symbol Pcyt1b
OMIM
CCDS CCDS30274
HPRD
IMGT
EMBL AK032027 AK053577 AK149304 AY189949 AY189950 BC048917
GenPept AAH48917 AAO39004 AAO39005 BAC27658 BAC35435 BAE28801

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca