Version 5.4
Mus musculus Protein: Pard3b
Summary
InnateDB Protein IDBP-159833.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pard3b
Protein Name par-3 partitioning defective 3 homolog B (C. elegans)
Synonyms 1810008K04Rik; 2010002N16Rik; 2810455B10Rik; Als2cr19; PAR3B; PAR3beta; PAR3L;
Species Mus musculus
Ensembl Protein ENSMUSP00000074837
InnateDB Gene IDBG-159823 (Pard3b)
Protein Structure
UniProt Annotation
Function Putative adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions (By similarity). {ECO:0000250}.
Subcellular Localization Endomembrane system {ECO:0000250}. Cell junction {ECO:0000250}. Cell junction, tight junction {ECO:0000250}. Note=Partially localized along the cell-cell contact region. Colocalizes with TJP1 to epithelial tight junctions (By similarity). {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0007049 cell cycle
GO:0008150 biological_process
GO:0051301 cell division
Cellular Component
GO:0005575 cellular_component
GO:0005923 tight junction
GO:0012505 endomembrane system
GO:0016020 membrane
Protein Structure and Domains
PDB ID MGI:1919301
InterPro IPR001478 PDZ domain
IPR021922 Protein of unknown function DUF3534
PFAM PF00595
PF13180
PF12053
PRINTS
PIRSF
SMART SM00228
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9CSB4
PhosphoSite PhosphoSite-Q9CSB4
TrEMBL
UniProt Splice Variant
Entrez Gene 72823
UniGene Mm.35153
RefSeq NP_001074519
MGI ID 1WG6
MGI Symbol Pard3b
OMIM
CCDS CCDS48276
HPRD
IMGT
EMBL AK013352 AL645544 AL645669 AL645727 AL662815 AL662920
GenPept BAB28805 CAI24504 CAI24824 CAI25199 CAI25349 CAI26112

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca