InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Mogs

Summary

InnateDB Protein

IDBP-160147.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Mogs

Protein Name

mannosyl-oligosaccharide glucosidase

Synonyms

1810017N02Rik; AI181835; Gcs1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000032114

InnateDB Gene

IDBG-160145 (Mogs)

Protein Structure

UniProt Annotation

Function

Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor. {ECO:0000250}.

Subcellular Localization

Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.

Experimentally validated
Total	10 [view]
Protein-Protein	10 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	13 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0003824	catalytic activity
GO:0004573	mannosyl-oligosaccharide glucosidase activity

Biological Process

GO:0009311

oligosaccharide metabolic process

Cellular Component

GO:0005789	endoplasmic reticulum membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

MGI:1929872

InterPro

IPR004888 Glycoside hydrolase, family 63
IPR008928 Six-hairpin glycosidase-like

PFAM

PF03200

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q80UM7

PhosphoSite

PhosphoSite-Q80UM7

TrEMBL

Q3U950

UniProt Splice Variant

Entrez Gene

57377

UniGene

Mm.399664

RefSeq

NP_065644

MGI ID

MGI Symbol

Mogs

OMIM

CCDS

CCDS20273

HPRD

IMGT

EMBL

AF001797 AK151941 BC051949

GenPept

AAD00906 AAH51949 BAE30817