Version 5.4
Mus musculus Protein: Ino80b
Summary
InnateDB Protein IDBP-160227.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ino80b
Protein Name INO80 complex subunit B
Synonyms 2510009I23Rik; HMG1YL4; Hmga1l4; Papa1; Znhit4;
Species Mus musculus
Ensembl Protein ENSMUSP00000032109
InnateDB Gene IDBG-160225 (Ino80b)
Protein Structure
UniProt Annotation
Function Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. {ECO:0000250}.
Subcellular Localization Nucleus, nucleolus {ECO:0000269PubMed:15556297}.
Disease Associations
Tissue Specificity Expressed strongly in the testis and moderately in the kidney, skeletal muscle, liver and lung. {ECO:0000269PubMed:15556297}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 23 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0008150 biological_process
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0031011 Ino80 complex
Protein Structure and Domains
PDB ID MGI:1917270
InterPro IPR006880 INO80 complex subunit B-like conserved region
IPR007529 Zinc finger, HIT-type
PFAM PF04795
PF04438
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q99PT3
PhosphoSite PhosphoSite-Q99PT3
TrEMBL
UniProt Splice Variant
Entrez Gene 70020
UniGene Mm.27814
RefSeq NP_076036
MGI ID
MGI Symbol Ino80b
OMIM
CCDS CCDS39530
HPRD
IMGT
EMBL AB054537 AK010946 BC019383 BC058788
GenPept AAH19383 AAH58788 BAB21110 BAB27284

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca