InnateDB Protein
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IDBP-160417.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Poglut1
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Protein Name
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protein O-glucosyltransferase 1
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000038166
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InnateDB Gene
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IDBG-160415 (Poglut1)
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Protein Structure
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Function |
Dual specificity glycosyltransferase. Catalyzes the transfer of glucose and xylose from UDP-glucose and UDP-xylose, respectively, to EGF repeats, such as those found in F7, F9 and NOTCH2, on the consensus sequence C-X-S-X-P-C. Positively regulates Notch signaling without affecting Notch ligand binding. {ECO:0000269PubMed:21949356}.
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Subcellular Localization |
Endoplasmic reticulum lumen {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Widely expressed in newborn and adult tissues (at protein level). {ECO:0000269PubMed:21490058}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated |
Total |
1
[view]
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Protein-Protein |
1
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
2 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:2444232
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InterPro |
IPR006598
Lipopolysaccharide-modifying protein
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PFAM |
PF05686
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PRINTS |
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PIRSF |
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SMART |
SM00672
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TIGRFAMs |
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Modification |
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SwissProt |
Q8BYB9
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PhosphoSite |
PhosphoSite-Q8BYB9
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TrEMBL |
Q8BLG5
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UniProt Splice Variant |
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Entrez Gene |
224143
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UniGene |
Mm.284366
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RefSeq |
NP_759012
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MGI ID |
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MGI Symbol |
Poglut1
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OMIM |
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CCDS |
CCDS28170
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HPRD |
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IMGT |
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EMBL |
AK031608
AK035948
AK036224
AK041321
AK045278
AK167641
BC026809
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GenPept |
AAH26809
BAC27475
BAC29255
BAC29351
BAC30905
BAC32292
BAE39692
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