InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Rpp30

Summary

InnateDB Protein

IDBP-160450.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rpp30

Protein Name

ribonuclease P/MRP 30 subunit (human)

Synonyms

Rnasep2; TSG15;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000025714

InnateDB Gene

IDBG-160448 (Rpp30)

Protein Structure

UniProt Annotation

Function

Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

Subcellular Localization

Nucleus, nucleolus {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	12 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004526	ribonuclease P activity
GO:0004540	ribonuclease activity
GO:0044822	poly(A) RNA binding

Biological Process

GO:0008033	tRNA processing
GO:0008150	biological_process
GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic

Cellular Component

GO:0005575	cellular_component
GO:0005730	nucleolus

Protein Structure and Domains

PDB ID

MGI:1859683

InterPro

IPR002738 RNase P subunit p30
IPR016195 Polymerase/histidinol phosphatase-like

PFAM

PF01876

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O88796

PhosphoSite

PhosphoSite-O88796

TrEMBL

Q8K238

UniProt Splice Variant

Entrez Gene

54364

UniGene

RefSeq

NP_062301

MGI ID

MGI Symbol

Rpp30

OMIM

CCDS

CCDS29770

HPRD

IMGT

EMBL

AK160536 AK169253 BC034329 U95123

GenPept

AAC24115 AAH34329 BAE35853 BAE41017