Version 5.4
Mus musculus Protein: Hectd2
Summary
InnateDB Protein IDBP-160764.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Hectd2
Protein Name HECT domain containing 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000042646
InnateDB Gene IDBG-160762 (Hectd2)
Protein Structure
UniProt Annotation
Function Probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0016874 ligase activity
Biological Process
GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:2442663
InterPro IPR000569 HECT
PFAM PF00632
PRINTS
PIRSF
SMART SM00119
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8CDU6
PhosphoSite PhosphoSite-Q8CDU6
TrEMBL Q8C9P8
UniProt Splice Variant
Entrez Gene 226098
UniGene Mm.61107
RefSeq NP_766225
MGI ID
MGI Symbol Hectd2
OMIM
CCDS CCDS29773
HPRD
IMGT
EMBL AC113514 AC119947 AK029549 AK035511 AK041629 AK043646
GenPept BAC26510 BAC29085 BAC31012 BAC31605

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca