Version 5.4
| Mus musculus Protein: Stard8 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Summary | |||||||||
| InnateDB Protein | IDBP-161717.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Stard8 | ||||||||
| Protein Name | START domain containing 8 | ||||||||
| Synonyms | |||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000044491 | ||||||||
| InnateDB Gene | IDBG-161715 (Stard8) | ||||||||
| Protein Structure |
|
||||||||
| UniProt Annotation | |||||||||
| Function | Accelerates GTPase activity of RHOA and CDC42, but not RAC1. Stimulates the hydrolysis of phosphatidylinositol 4,5- bisphosphate by PLCD1 (By similarity). {ECO:0000250}. | ||||||||
| Subcellular Localization | Cell junction, focal adhesion {ECO:0000269PubMed:17976533}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | |||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
|
||||||||
| Gene Ontology | |||||||||
Molecular Function |
|
||||||||
| Biological Process |
|
||||||||
| Cellular Component |
|
||||||||
| Protein Structure and Domains | |||||||||
| PDB ID | MGI:2448556 | ||||||||
| InterPro |
IPR000198
Rho GTPase-activating protein domain IPR002913 START domain IPR008936 Rho GTPase activation protein |
||||||||
| PFAM |
PF00620
PF01852 |
||||||||
| PRINTS | |||||||||
| PIRSF | |||||||||
| SMART |
SM00324
SM00234 |
||||||||
| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q8K031 | ||||||||
| PhosphoSite | PhosphoSite-Q8K031 | ||||||||
| TrEMBL | B1AZJ1 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 236920 | ||||||||
| UniGene | Mm.489453 | ||||||||
| RefSeq | NP_950183 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Stard8 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS30297 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AK133927 AK149830 AK150259 AK172910 AL672103 AL954636 BC023434 BC034186 BC062944 | ||||||||
| GenPept | AAH23434 AAH34186 AAH62944 BAD32188 BAE21930 BAE29110 BAE29418 CAM26794 | ||||||||