InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Rexo2

Summary

InnateDB Protein

IDBP-162038.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rexo2

Protein Name

REX2, RNA exonuclease 2 homolog (S. cerevisiae)

Synonyms

1810038D15Rik; AW107347; Sfn; Smfn;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000034524

InnateDB Gene

IDBG-162036 (Rexo2)

Protein Structure

UniProt Annotation

Function

3'-to-5' exoribonuclease specific for small oligoribonucleotides. Active on small (primarily

Subcellular Localization

Mitochondrion intermembrane space {ECO:0000250}. Mitochondrion matrix {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0004527	exonuclease activity
GO:0008408	3'-5' exonuclease activity

Biological Process

GO:0006139	nucleobase-containing compound metabolic process
GO:0090305	nucleic acid phosphodiester bond hydrolysis

Cellular Component

GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005739	mitochondrion
GO:0005758	mitochondrial intermembrane space
GO:0005759	mitochondrial matrix
GO:0005886	plasma membrane
GO:0005925	focal adhesion