InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Nudcd2

Summary

InnateDB Protein

IDBP-163362.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Nudcd2

Protein Name

NudC domain containing 2

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000020578

InnateDB Gene

IDBG-163360 (Nudcd2)

Protein Structure

UniProt Annotation

Function

May regulate the LIS1/dynein pathway by stabilizing LIS1 with Hsp90 chaperone. {ECO:0000250}.

Subcellular Localization

Chromosome, centromere, kinetochore {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000250}. Note=Associates with centrosomes in interphase and to spindle poles and kinetochores during mitosis. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 38 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	38 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0005515	protein binding

Biological Process

GO:0008150

biological_process

Cellular Component

GO:0000777	condensed chromosome kinetochore
GO:0000922	spindle pole
GO:0005622	intracellular
GO:0005737	cytoplasm
GO:0005815	microtubule organizing center
GO:0015630	microtubule cytoskeleton
GO:0070062	extracellular vesicular exosome